Background: The evaluation of asthma among the pediatric population is often challenging. Tidal breathing analysis has been available for decades in both clinical and research settings as means to indirectly measure the airway mechanics. This study aims to determine the lung function of children less than 6 years old suspected with asthma using tidal breathing analysis.
Method: This is a cross-sectional analytical study. A total of 35 subjects were classified as to viral-induced wheeze, doubtful asthma and probable asthma based on the questionnaire adopted from the 2017 GINA guidelines. TPTEF/TE was measured using Jaeger Masterscreen Baby Body Paediatrics System.
Results and Discussion: The results of this study showed that there was a difference in TPTEF/TE of children less than 6 years old based on asthma-like symptoms. A significant difference was noted when the tidal breathing analysis of children with doubtful asthma was compared to either the children with viral induced wheeze or children with probable asthma. However, no significant difference was noted in the tidal breathing analysis of children with viral induced wheeze and with probable asthma.
Conclusion: A TPTEF/TE of 29.68 ± 11.89 can be used as a reference value for patients suspected with asthma. These reference data can be used as a valuable tool in the clinical application of tidal breathing analysis for diagnosing asthma among the pediatric population. However, it does not delineate the TBA values expected for normal subjects, which is the major limitation of this study.