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HERDIN Record #: PCHRD1705160853239 Submitted: 16 May 2017 Modified: 16 May 2017

The first MIBG therapy in the Philippines.

Patricia A. Bautista,
Jonas Francisco Y. Santiago

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Neuroblastoma is an embryonal tumor of children that frequently presents with metastases. Our patient is a 6-year-old girl who was diagnosed to have neuroblastoma with diffuse metastatic disease throughout the skeleton as seen in her 123I-MIBG scan in the United States. 18F-FDG PET/CT scan was done in the Philippines after chemotherapy and gene therapy, and before 131I-MIBG therapy. No additional lesions were seen on PET.  131I-MIBG was then performed and an 131I-MIBG with SPECT/CT thereafter, which showed an increase in size and extent of the lesion in the head and a decrease in number of the skeletal metastases. New 131I-MIBG-avid posterior cervical lymph nodes were also localized through SPECT/CT. For this patient, a follow-up 123I/131I-MIBG scan would be more cost-effective in assessing response to therapy. Sectional imaging may be done to obviate the need for sedation of this young patient.

Publication Type
Publication Sub Type
Case report
The Philippine Journal of Nuclear Medicine
Publication Date
January-June 2015
LocationLocation CodeAvailable FormatAvailability
Philippine Council for Health Research and Development Library Box No.21 Fulltext Print Format

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