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HERDIN Record #: PCHRD17012008221964 Submitted: 20 January 2017 Modified: 19 January 2018

Relapsing polychondritis initially presenting with hoarseness and difficulty breathing in a 21-year-old male.

Paula Francezca Padua,

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OBJECTIVE: To present a case of relapsing polychondritis initially presenting with hoarseness and difficulty breathing and to discuss the diagnostic criteria and typical CT scan findings of relapsing polychondritis.
Design: Case Report
Setting: Tertiary Private Hospital in Metro Manila
Patient: One
RESULT: A 21-year-old man who was initially managed as a case of bronchial asthma for persistent hoarseness and recurrent difficulty breathing was found to have severe laryngeal edema on endoscopy, and soft tissue expansion of the cricoid cartilage with calcifications and irregular first tracheal ring on CT scan. He also had recurrent eye redness and developed bilateral aural inflammation, and was subsequently diagnosed to have relapsing polychondritis.
CONCLUSION: Relapsing polychondritis is a rare autoimmune disease characterized by recurrent inflammation and eventual destruction of cartilage throughout the body. Typical manifestations may not always be present, causing a delay in diagnosis. It should be considered in patients with intractable respiratory symptoms not responsive to treatment for upper respiratory tract infections or asthma. A CT scan may reveal signs of cartilage destruction and help in diagnosis.                 

Publication Type
Publication Sub Type
Journal Article, Original
Philippine Journal of Otolaryngology Head and Neck Surgery
Publication Date
July-December 2016
LocationLocation CodeAvailable FormatAvailability
Philippine Council for Health and Research Development Box No. 64 Abstract Print Format
Philippine Council for Health Research and Development Fulltext pdf (Request Document)
1. Vitale, A , Sota, J , Rigante, D , Lopalco, G , Molinaro, F , Messina, M. . "Relapsing polychondritis: An update on pathogenesis, clinical features, diagnostic tools, and therapeutic perspectives" Pubmed 18(1): January 2016. Retrieved from: http://DOI:10.1007/S11926-015-0549-5PubMedPMID:26711694.

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