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HERDIN Record #: NCR-PHC-16041917460713 Submitted: 20 April 2016 Modified: 20 April 2016

Association Between Diastolic Dysfunction Severity by Doppler Echocardiography and Significant Coronary Artery Disease by Coronary Angiography: A Descriptive Study.

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Introduction: Diastolic dysfunction (DD) refers to abnormalities in LV filling secondary to altered compliance, relaxation, and/or recoil. The prevalence of diastolic dysfunction is greater than that of systolic dysfunction and is increased with aging. For the past years, much attention has been given to LV systolic function as an independent marker  for severity of coronary artery disease, creating much emphasis on this parameter. However, it has also been recognized that left ventricular diastolic dysfunction is an important clinical parameter which is associated with a substantial risk of subsequent development of congestive heart failure and reduced survival of patients similar to what happpens in systolic dysfunction. This study ventured in the existence of a direct association between the severity of diastolic dysfunction using doppler echocardiography with the number of angiographically significant coronary artery lesions seen on coronary angiography.

Methods: This is a descriptive study employing a retrospective approach of patients' chart review. Patients aged ≥19 years old with baseline 2D echocardiography with doppler studies who underwent coronary angiograpy admitted at the Philippine Heart Center from January 2014- January 2015 were included. Spearman's Correlation Test was utilized for analysis.

Results: There was a direct but weak correlation between the severity of diastolic dysfunction on doppler echocardiography and the number of coronary arteries with significant lesions on coronary angiography, although it was deemed not statistically significant.

Conclusion: Although a direct correlation exists between DD severity on doppler echocardiography and the number of angiographically significant coronary artery lesions, other factors such as age, comorbidities, miscrovascular coronary disease and inherent intracellular myocardial abnormalities contribute to the poor prognosis observed among these subset of patients.

Publication Type
Research Project
LocationLocation CodeAvailable FormatAvailability
Philippine Heart Center Medical Library PHC.IR.008.15 Fulltext Print Format

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