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HERDIN Record #: PCHRD08171108080216 Submitted: 17 August 2011 Modified: 26 April 2018

Phase II Clinical study: Comparative, randomized, double-blind trial of Vitex negundo L. (lagundi) syrup among pediatric patients with non-bacterial acute cough of moderate severity.

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There were 214 pediatric patients screened and 66 were included; 32 in Group 2 and 34 in Group 3. Based on age, the subjects were mostly 6-10 years (39/66 or 59%) with 18.2% each in 0-5 and 11-15 years and 4.6% were between 16-20 years old. The mean age was 8.3 years for both groups among those completed treatment.

The drop-out rate was 22% (7/32) for Group 2 and 24% (8/34) for Group 3 with 26 patients completing therapy.

As to response to therapy, there were 20/26 or 75.9% who responded in Group 2 and 81% (21/26) in Group 3. Initial statistical analysis showed no significant differences in the two groups (Placebo and high dose Lagundi Syrup) based on drop-out rate, non-response and good response to therapy after 8 days treatment. (Author)


Phase II: Clinical stusies done in lagundi tablet as anticough.

Publication Type
Research Project
LocationLocation CodeAvailable FormatAvailability
Philippine Council for Health Research and Development Library Abstract Print Format
Philippine Council for Health Research and Development Fulltext Print Format

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