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Results 51 - 60 of 758

Validation of IKPaB: Filipino version of Children's Dermatology Life Quality Index (CDLQI) text version

Implementing Agency
Philippine General Hospital, Section of Dermatology
Project Description
This is a two-part, cross-sectional survey using a self-administered questionnaire to assess the validity and reliability of Indeks ng Kalidad ng Buhay Pang-dermatolohiya ng mga Bata (IKPaB), a Filipino translation of the Children’s Dermatology Life Quality Index (CLDQI) text version.
Date of Registration
02 September 2013
Region
NCR
Sources of Monetary or Material Support
Self-funded
Primary Outcomes
Internal consistency reliability, construct and criterion validity
Health Condition(s) or Problem(s) Studied
Children with skin conditions

Semen PCR for testicular tumor

Implementing Agency
Philippine General Hospital, Department of Surgery
Project Description
This is a pilot study designed to be a prospective, blind comparison to a gold standard study that will include consecutive patients who consult, or are referred to the Urology service of the Philippine General Hospital for a testicular mass. It aims to determine if the polymerase chain reaction amp . . .
Cooperating Sponsor
Philippine Urological Association
Date of Registration
03 September 2013
Region
NCR
Sources of Monetary or Material Support
National Institutes of Health - University of the Philippines - Manila
Philippine Urological Association
Primary Outcomes
A preliminary study on the clinical utility of PCR for Tuberculosis from semen samples as preoperative screening for tuberculous orchitis among patients clinically diagnosed with testicular tumor. After 2 collection of semen samples collected 4-14 days apart. This is a pilot study designed to be a p . . .
Health Condition(s) or Problem(s) Studied
Testicular tumor, testicular tuberculosis, testicular cancer

Prevalence of Onychomycosis and other Nail Changes among Patients with Psoriasis and other Skin Diseases seen at Philippine General Hospital: A Cross-sectional Study

Implementing Agency
Philippine General Hospital, Section of Dermatology
Project Description
Psoriasis is a chronic distressing skin disease that affects millions of people. One of its commonly overlooked manifestations is the presence of nail changes, which is often confused with fungal infections. The two diseases may predispose the development of one another. The dystrophy in psoriatic n . . .
Date of Registration
03 September 2013
Region
NCR
Sources of Monetary or Material Support
Self-funded
Philippine Urological Association
Primary Outcomes
number of patients diagnosed to have onychomycosis
Health Condition(s) or Problem(s) Studied
psoriasis, onychomycosis

Phase 3, Open-Label, Baseline-controlled, Multi-center, Sequential Dose-Titration Study to Assess the Pharmacokinetics, Long-Term Efficacy and Safety of Solifenacin Succinate Suspension in Children From 2 Years to Less Than 5 Years of Age with Neurogenic Detrusor Overactivity

Implementing Agency
Astellas Pharma Europe B.V.
Project Description
This study is a phase 3, open-label, baseline-controlled, sequential dose titration study to assess the pharmacokinetics, long-term efficacy and safety of Solifenacin Succinate suspension in children from 2 years to less than 5 years of age with neurogenic detrusor overactivity (NDO). Solifenaci . . .
Cooperating Sponsor
PPD Development (S) PTE. LTD.
Date of Registration
02 September 2013
Region
Netherlands
Sources of Monetary or Material Support
Astellas Pharma Europe B.V.
Philippine Urological Association
Primary Outcomes
Primary efficacy variable: Change from baseline in maximum cystometric capacity (MCC) during treatment at week 24.
Health Condition(s) or Problem(s) Studied
Neurogenic Detrusor Overactivity

Medicinal properties of purple yam and manunggal

Implementing Agency
Visayas State University
Project Description
PRP-1 (PhilRootcrops Protein-1) is a naturally-derived angiotensin-converting-enzyme (ACE) inhibitor from yam. Likewise, manunggal is a folkloric medicinal plant that is popularly used by herbal practitioners for treatment of chronic metabolic diseases. The number of people suffering from hypertensi . . .
Date of Registration
13 September 2013
Region
Region VIII
Sources of Monetary or Material Support
DOST Central Office
Philippine Urological Association
Primary Outcomes
data on the antidiabetic and antihypertensive properties of PRP-1 from purple yam and manunggal
Health Condition(s) or Problem(s) Studied
diabetes and hypertension

A 52-week treatment, multi-center, randomized, doubleblind, double dummy, parallel-group, active controlled study to compare the effect of QVA149 (indacaterol maleate / glycopyrronium bromide) with salmeterol/fluticasone on the rate of exacerbations in subjects with moderate to very severe COPD

Implementing Agency
Novartis Healthcare Philippines, Inc.
Project Description
Study of efficacy and safety of QVA149 compared to salmeterol/fluticasone active comparator in patients with COPD. The purpose of the study is to compare the effect of a fixed dose combination of a LABA/LAMA, (QVA149 110/50 μg o.d.) and combination of a LABA/ICS (salmeterol/fluticasone 50/500 μg b . . .
Date of Registration
06 January 2014
Region
NCR
Sources of Monetary or Material Support
Novartis Healthcare Philippines, Inc.
Philippine Urological Association
Primary Outcomes
To demonstrate that QVA149 (110/50 μg o.d.) is at least noninferior to salmeterol/fluticasone (50/500 μg b.i.d.) in terms of rate of COPD exacerbations (mild/moderate/severe) during 52 weeks of treatment.
Health Condition(s) or Problem(s) Studied
Chornic Obstructive Pulmonary Disease (COPD)

The efficacy and safety of topical papaya (Carica papaya) leaf extract 1% ointment versus mupirocin 2% ointment in the treatment of limited impetigo: a randomized, double-blind, controlled clinical trial

Implementing Agency
St. Luke's Medical Center, Department of Dermatology
Project Description
This study will be an investigator-blinded, patient-blinded, assessor-blinded, parallel-group, randomized clinical trial. It aims to evaluate the efficacy of one-week twice-daily application of topical papaya leaf extract ointment compared to mupirocin ointment in achieving clinical cure among patie . . .
Date of Registration
23 September 2013
Region
NCR
Sources of Monetary or Material Support
St. Luke's Medical Center, Research and Biotechnology Division
Philippine Urological Association
Primary Outcomes
Clinical clearance after 1 week of treatment
Health Condition(s) or Problem(s) Studied
Impetigo

Antimicrobial and Antiparasitic Constituent(s) of Moringa oleifera Lam

Implementing Agency
University of the Philippines - Diliman, Institute of Chemistry
Project Description
The project aims to study the leaf extracts of M. oleifera for its antibacterial activities against Escherichia coli, Salmonella typhimurium, Pseudomonas aeruginosa, and Staphylococcus aureus, its antifungal activity against Candida albicans, and its antiparasitic activities against Trichomonas vagi . . .
Cooperating Sponsor
University of the Philippines - Diliman, Institute of Biology
Date of Registration
21 October 2013
Region
NCR
Sources of Monetary or Material Support
Philippine Council for Health Research and Development, Department of Science and Technology
Philippine Urological Association
Health Condition(s) or Problem(s) Studied
Bacterial Infections, Fungal Infections, Parasitic Diseases

The Prevalence of Common Oral Disease Among 3-5 Years old Pre-school Children

Implementing Agency
University of the Philippines - Manila, College of Dentistry
Project Description
The study will describe the most common oral disease among 3-5 years old pre-school children in public daycare centers in the municipality of San Juan, Batangas
Date of Registration
25 September 2013
Region
NCR
Sources of Monetary or Material Support
National Institutes of Health - University of the Philippines - Manila
Philippine Urological Association
Primary Outcomes
The primary outcome measures will be the common oral disease as measured by the deft (decayed, extracted, filled teeth) and pufa (pulp involvement, ulceration, fistula, abscess) indices.
Health Condition(s) or Problem(s) Studied
Prevalence common oral disease among 3-5 years old preschool children in public day care centers

A phase IIIb, multicenter, multinational, randomized, double-blind, placebo controlled, parallel group study to evaluate the glycemic and renal efficacy of once daily administration of linagliptin 5 mg for 24 weeks in type 2 diabetes patients, with micro- or macroalbuminuria (30-3000mg/g creatinine) on top of current treatment (with Angiotensin Converting Enzyme inhibitor or Angiotensin Receptor Blocker) – MARLINA (Efficacy, safety & Modification of Albuminuria in type 2 diabetes subjects with Renal disease with LINAgliptin)

Implementing Agency
Boehringer Ingelheim Singapore, Pte. Ltd.
Project Description
Evaluate linagliptin in terms of glycemic control as defined by HbA1c after 24 weeks of treatment and in terms of renal efficacy as defined by changes in albuminuria (UACR) after 24 weeks of treatment.
Date of Registration
01 October 2013
Region
Singapore
Sources of Monetary or Material Support
Boehringer Ingelheim Singapore, Pte. Ltd.
Philippine Urological Association
Primary Outcomes
To investigate the glycemic efficacy and safety of linagliptin 5 mg given orally once daily for 24 weeks to type 2 diabetes patients with albuminuria (urinary albumin-to-creatinine ratio 30-3000 mg/g creatinine) on top of current therapy.
Health Condition(s) or Problem(s) Studied
Diabetes Mellitus, Type 2

Results 51 - 60 of 758
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