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Results 41 - 50 of 1105

Safety and immunogenicity of Recombinant COVID-19 vaccine  as a booster following primary vaccination of either Inactivated or mRNA or Viral Vector COVID-19 vaccines: A phase II observer-blind, randomized, controlled, investigator-initiated clinical trial

Implementing Agency
WestVac Biopharma Co., Ltd.
Project Description
This is a Phase II observer-blind randomized controlled trial to evaluate the safety and immunogenicity of Recombinant COVID-19 vaccine  (SF9 cells) booster vaccination following primary vaccination of either Inactivated or mRNA or Viral Vector COVID-19 vaccines produce . . .
Date of Registration
20 June 2022
Region
China
Sources of Monetary or Material Support
WestVac Biopharma Co., Ltd.
Primary Outcomes
Primary endpoints Safety Incidence of adverse drug reactions (ADRs) 0 to 28 days after a booster dose. Immunogenicity Geometric mean titer (GMT) of specific neutralizing antibody (Virus or Pseudovirus Neutralizatio . . .
Health Condition(s) or Problem(s) Studied

Prevention of COVID-19 caused by infection with the SARS-CoV-2.


Mindfulness-Based Self-Compassion Therapy as an Adjunct Treatment for Moderate to Severe Chronic Plaque Psoriasis: A Randomized Control Trial

Implementing Agency
Rizal Medical Center Department of Dermatology
Project Description
Purpose of the researchReducing stress through mindfulness may lead to improvement of the skin lesions in psoriasis. The results of the study may benefit patients by providing patients with alternatives that have long-term effects as compared to the known standard treatments. The results of . . .
Date of Registration
21 June 2022
Region
NCR
Sources of Monetary or Material Support
Rizal Medical Center Department of Dermatology
Primary Outcomes

Psoriasis Area Severity Index

Dermatology Life Quality Index

Health Condition(s) or Problem(s) Studied

Chronic Plaque Psoriasis


A 5-year study to test BI 655130 in patients with Generalized Pustular Psoriasis who took part in previous studies with BI 655130

Implementing Agency
Boehringer Ingelheim (Philippines), Inc.
Project Description
This open label, non-randomised multi-regimen, 5-year extension study investigates the long-term safety and efficacy of BI 655130 in patients (adult and adolescent) with Generalized Pustular Psoriasis (GPP) who have completed their participation in previous BI 655130 trials 1368-0013 or 1368-0027 . . .
Cooperating Sponsor
PAREXEL Clinical Research (Philippines) Ltd. Corp.
Date of Registration
25 November 2021
Region
NCR
Sources of Monetary or Material Support
Boehringer Ingelheim Singapore, Pte. Ltd.
Primary Outcomes

Primary objective: to evaluate the long-term safety and efficacy of BI 655130 in patients with GPP, who have completed previous BI 655130 trials

Primary endpoint: occurrence of treatment emergent adverse events (TEAEs) up to week 252 of maintenance treatment.

Health Condition(s) or Problem(s) Studied

Generalized Pustular Psoriasis (GPP)


A 10-Year Retrospective Study of Surgical Outcomes of Pediatric Patients with Frontal Encephalocoele in Southern Philippines Medical Center, Davao City, Philippines

Implementing Agency
SPMC
Project Description
Southern Philippines Medical Center is the only tertiary hospital in Southern Philippines that cater to most of the difficult and rarest cases in Mindanao. Given this, the study aims to provide an overview regarding the prevalence of frontal encephalocoele in Southern Philippines and describe the . . .
Cooperating Sponsor
SPMC
Date of Registration
26 August 2022
Region
Region XI
Sources of Monetary or Material Support
Self-funded
Primary Outcomes

The sociodemographic data gathered will be encoded in a Microsoft Word document with a pre-made tabulation of the study’s raw data. Baseline description of the patients’ characteristics using means, percentages and standard deviations will be computed using Epi Info Statistical Software.

Health Condition(s) or Problem(s) Studied

all chart data from pediatric patients who underwent repair of frontal encephalocoele will be included from January 2006 to September 2019.


CORRELATION OF CYTOMORPHOLOGY WITH FLOW CYTOMETRY IN THE INITIAL DIAGNOSIS OF ACUTE LEUKEMIA IN CHILDREN IN SOUTHERN PHILIPPINES MEDICAL CENTER

Implementing Agency
Southern Philiipines Medical Center
Project Description
Acute leukemia is the most common childhood cancer worldwide. The diagnosis of acute leukemia requires the integration of hematopathological diagnosis depending on studies of cell morphology and application of flow cytometry according to WHO classification. There are times that morphological diag . . .
Date of Registration
23 June 2022
Region
Philippines
Sources of Monetary or Material Support
Southern Philiipines Medical Center
Primary Outcomes

Concordance and discordance of cytomorphology and flow cytometry

Health Condition(s) or Problem(s) Studied

Concordance of bone marrow morphology with flow cytometry in SPMC


A Multi-center, Observer-blind, Randomized, Controlled Phase 3 Study to Evaluate the Immunogenicity and Safety of Adjuvanted Recombinant SARS-CoV-2 Trimeric Sprotein Subunit Vaccine (SCB-2019), Administered as a Booster Dose to Adults, who Previously Received Primary Series of a COVID-19 Vaccine

Implementing Agency
Clover Biopharmaceuticals AUS Pty Ltd
Project Description
This is a multi-center, observer-blind, randomized, controlled phase 3 study to evaluate the immunogenicity and safety of SCB-2019 vaccine administered as a booster dose in individuals who received primary vaccination series with one of the selected COVID-19 vaccines, ≥3months prior to enrollme . . .
Cooperating Sponsor
Novotech (Australia) Pty. Ltd. - Philippine Branch
Date of Registration
11 July 2022
Region
None
Sources of Monetary or Material Support
Clover Biopharmaceuticals AUS Pty Ltd
Primary Outcomes

The primary endpoints are SARS-CoV-2-neutralization titers at Day 15 in SCB-2019 booster recipients and recipients of a homologous booster vaccine within each primary vaccination group (Comirnaty,
COVID-19 Vaccine Janssen, and CoronaVac).

Health Condition(s) or Problem(s) Studied

COVID 19


COMPARISSON OF ON DEMAND AND SCHEDULED TREATMENT INTERVAL FOR  DEB-TACE IN INTERMEDIATE STAGE HEPATOCELLULAR CARCINOMA:  A SYSTEMATIC REVIEW AND META-ANALYSIS

Implementing Agency
Southern Philippines Medical Center, Department of Radiological and Imaging Sciences
Project Description
This study aims to present a systematic review and meta-analysis to compare the safety, efficacy, and outcomes of on demand versus scheduled DEB-TACE in patients with intermediate stage HCC. Specifically, this study aims: To perform a systematic literature review of interva . . .
Date of Registration
03 June 2022
Region
Region XI
Sources of Monetary or Material Support
Self-funded
Primary Outcomes

Overall survival

Progression free interval

Health Condition(s) or Problem(s) Studied

Hepatocellular Carcinoma


Clinical Characteristics and Outcomes of Surgical Patients with Suspected or Confirmed Coronavirus Disease -19 (COVID-19) Infection

Implementing Agency
Southern Philippines Medical Center, Department of Anesthesiology
Project Description
The Principal Investigators would like to determine the clinical characteristics and outcomes of surgical patients with confirmed or suspected Covid 19 Infection. Specifically, to determine the demographic data of the patients (age, gender, ASA classification, COVID-19 test result), the anesthet . . .
Cooperating Sponsor
Southern Philippines Medical Center, Department of Anesthesiology
Date of Registration
20 July 2022
Region
Region XI
Sources of Monetary or Material Support
Self-funded
Primary Outcomes

 Mortality
 

 

Health Condition(s) or Problem(s) Studied

Clinical characteristics and outcomes of surgical patients with confirmed or suspected Covid 19 Infection


A Comparative Study on The Incidence of Infection in Open Tibia Fractures in Patients Admitted in SPMC During The COVID-19 Pandemic March 2021-December 2021 versus March 2019-December 2019

Implementing Agency
Southern Philippines Medical Center, Davao City, Philippines
Project Description

This study aims to compare if there is an increase in the incidence of infection in patients with open tibial fractures during the COVID pandemic March 2021-December 2021 versus March 2019 – December 2019

Cooperating Sponsor
Southern Philippines Medical Center, Davao City, Philippines
Date of Registration
11 May 2022
Region
Region XI
Sources of Monetary or Material Support
Southern Philippines Medical Center
Primary Outcomes

Increase in the incidence of surgical site infection of open tibial fractures

Health Condition(s) or Problem(s) Studied

This study aims to compare if there is an increase in the incidence of infection in patients with open tibial fractures during the COVID pandemic March 2021-December 2021 versus March 2019 – December 2019


CLINICAL OUTCOMES OF CHILDREN WITH HIV/AIDS ON ANTIRETROVIRAL THERAPY AT THE HIV/AIDS CENTER FOR TREATMENT (HACT) OF SOUTHERN PHILIPPINES MEDICAL CENTER FROM 2009 TO 2019

Implementing Agency
Southern Philippines Medical Center, Department of Pediatrics
Project Description
Title: CLINICAL OUTCOMES OF CHILDREN WITH HIV/AIDS ON ANTIRETROVIRAL THERAPY AT THE HIV/AIDS CENTER FOR TREATMENT (HACT) OF SOUTHERN PHILIPPINES MEDICAL CENTER FROM 2009 TO 2019 Author/s: IDA MARIONNE Q. ARRIOLA, MD, MPH and Consu . . .
Cooperating Sponsor
Southern Philippines Medical Center
Date of Registration
13 May 2022
Region
Region XI
Sources of Monetary or Material Support
Self-funded
Primary Outcomes
The clinical outcome of children with HIV/AIDS on antiretroviral therapy will be assessed at 6, 12 and 36 months with repeated CD4 and viral load measures. A review of information available in charts will be accessed, and demographic profiles such as age, sex, clinical stage upon diagnosi . . .
Health Condition(s) or Problem(s) Studied

Pediatric HIV/AIDS 

 


Results 41 - 50 of 1105
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