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Results 11 - 20 of 1105

A three-year, open-label extension study of subcutaneous secukinumab to evaluate the long-term efficacy, safety, and tolerability in patients with active lupus nephritis 

Implementing Agency
Novartis Healthcare Philippines, Inc.
Project Description
This three-year open-label extension study will offer continuous secukinumab therapy to eligible participants from the core study CAIN457Q12301 and will provide long-term efficacy and safety data. The proposal to continue treatment with subcutaneous (s.c.) doses of 300 mg administered every four . . .
Date of Registration
28 September 2022
Region
NCR
Sources of Monetary or Material Support
Novartis Healthcare Philippines, Inc.
Primary Outcomes

The primary objective is to assess long-term efficacy of secukinumab with respect to Complete Renal Response (CRR) over time up to Week 260 in adult participants with Lupus Nephritis (ISN/RPS Class III or IV, with or without co-existing class V features) on background SoC therapy 

Health Condition(s) or Problem(s) Studied

Lupus Nephritis


Strengthening Health Professions Education (HPEd) Through Appreciative Inquiry (AI) During the Pandemic

Implementing Agency
University of the Philippines Manila
Project Description
Rationale.  Appreciative Inquiry (AI) is a tool or an approach that can help people, from all walks of life, during crises such as the COVID-19 pandemic, to see the silver lining, the opportunities instead of the threats, and growth in the midst of dist . . .
Date of Registration
14 July 2022
Region
Philippines
Sources of Monetary or Material Support
University of the Philippines
Primary Outcomes
To identify the best experiences or significant experiences during practice of the health care workers during the COVID-19 pandemic, To analyze the health wor . . .
Health Condition(s) or Problem(s) Studied

The development of  instructional resources that will enable health professions educators to learn Appreciative Inquiry principles, approaches, and processes of which they can integrate in their teaching-learning processes, in managing and leading their own health organizations, and in mentoring/coaching their learners.


“CLINICAL PROFILE AND OUTCOME OF YOUNG PATIENTS WITH COLON CANCER AT THE SOUTHERN PHILIPPNES MEDICAL CENTER: A TEN-YEAR REVIEW

Implementing Agency
Southern Philippines Medical Center, Davao City, Philippines
Project Description

“CLINICAL PROFILE AND OUTCOME OF YOUNG PATIENTS WITH COLON CANCER AT THE SOUTHERN PHILIPPNES MEDICAL CENTER: A TEN-YEAR REVIEW

A RETROSPECTIVE DESCRIPTIVE STUDY

Cooperating Sponsor
Southern Philippines Medical Center
Date of Registration
30 August 2022
Region
Region XI
Sources of Monetary or Material Support
Southern Philippines Medical Center
Primary Outcomes

To determine the demographic and the clinical profiles associated among patients diagnosed with colorectal cancer ages 50 years and below at Southern Philippines Medical Center from the year 2011 to 2020

Health Condition(s) or Problem(s) Studied

Colorectal Cancer 


Clinical Profile and Outcome of Pediatric Hodgkin’s Lymphoma in a Tertiary Government Hospital

Implementing Agency
Southern Phiippines Medical Center
Project Description
Hodgkin's lymphoma is one of the six common cancer focus of the Global Initiative for Childhood Cancer that was launched by the World Health Organization and the Philippines is one of its focus countries.  Few studies assess the pattern of incidence, treatment outcomes, and survival for Hodgkin . . .
Cooperating Sponsor
Southern Philiipines Medical Center
Date of Registration
16 September 2022
Region
Region XI
Sources of Monetary or Material Support
Southern Phiippines Medical Center
Primary Outcomes

Clinical profile and treatment outcome 

Health Condition(s) or Problem(s) Studied

Pediatric Hodgkin’s Lymphoma


Trial of Sibeprenlimab in the Treatment of Immunoglobulin A Nephropathy

Implementing Agency
Otsuka Pharmaceutical Development and Commercialization, Inc.
Project Description

Multicenter, open-label trial to evaluate the long-term safety, tolerability, and efficacy of sibeprenlimab administered subcutaneously (SC) to subjects with IgAN.

Date of Registration
06 September 2022
Region
NCR
Sources of Monetary or Material Support
Otsuka Pharmaceutical Development and Commercialization, Inc.
Primary Outcomes

Safety and Tolerability

Health Condition(s) or Problem(s) Studied

Immunoglobulin A Nephropathy


Global Study on the Clinical Detection Performance and Usefulness of Novel Coronavirus Rapid Diagnostic Kit

Implementing Agency
National Center for Global Health and Medicine
Project Description
This study aims to examine the usability of a novel Rapid Antigen Test kit in diagnosing SARS-CoV-2. The accuracy of the test kit result will be evaluated and compared with plate-based polymerase chain reaction result in swab specimens collected. This study will also examine whether the test ki . . .
Cooperating Sponsor
University of the Philippines - Philippine General Hospital, Department of Laboratories
Date of Registration
23 September 2022
Region
Japan
Sources of Monetary or Material Support
National Center for Global Health and Medicine
Primary Outcomes

The agreement rate between the test results of RT-PCR test and the Rapid Antigen Test.

Health Condition(s) or Problem(s) Studied

To verify that the ESPLINE SARS-CoV-2 (Fuji Rebio, Co. Ltd, Japan) has comparable clinical detection performance to that of RT-PCR, an existing nucleic acid detection test. The following concerns with consideration of the usefulness of the kit as a routine test due to its versatility will be addressed by testing nasopharyngeal swab specimens from participants suspected of the novel coronavirus, SARS-CoV-2 infection.


RELATIONSHIP OF HYPOCALCEMIA WITH DISEASE SEVERITY AND OUTCOME IN PATIENTS WITH COVID-19

Implementing Agency
Southern Philiipines Medical Center
Project Description
This study aims to not replace testing in determining severity of COVID-19, but to use it as predictor for disease severity and predict outcomes such as recovery or death. This study aims to show the relationship of hypocalcemia and disease severity in patients with Cov . . .
Date of Registration
30 July 2022
Region
Philippines
Sources of Monetary or Material Support
Southern Philippines Medical Center, Davao City, Philippines
Primary Outcomes

Determine presence of disease severity in patients with hypocalcemia and COVID-19.

Determine presence of ARDS associated with hypocalcemia and COVID-19.

Health Condition(s) or Problem(s) Studied

COVID-19 Infection


EFFECTS ON POST-OPERATIVE PAIN REDUCTION IN CESAREAN SECTIONS (LOW MIDLINE INCISION) WITH THE USE OF CRYOTHERAPY: A RANDOMIZED CONTROL TRIAL

Implementing Agency
Corazon Locsin Montelibano Memorial Regional Hospital
Project Description

This study aims to determine the post-operative pain reduction by adding cryotherapy to the standard postoperative pain management in cesarean sections (low midline incision) among patients in Corazon Locsin Montelibano Memorial Regional Hospital.

Cooperating Sponsor
Corazon Locsin Montelibano Memorial Regional Hospital
Date of Registration
12 July 2022
Region
Region VI
Sources of Monetary or Material Support
Corazon Locsin Montelibano Memorial Regional Hospital
Primary Outcomes
The primary outcome in this study is the postoperative pain reduction by cryotherapy together with the standard post-operative pain management versus without among patients who underwent obstetric low midline incision surgeries in CLMMRH. Any observable result pattern . . .
Health Condition(s) or Problem(s) Studied

The information derived from this research shall form part of an integral data base that could help guide future researches with the use of adding a non-pharmacologic treatment and it’s benefits in obstetric postoperative pain management.

 


EVALUATION OF FINE NEEDLE BIOPSY (FNB) FOR EUS GUIDED TISSUE ACQUISITION OF PANCREATIC MASSES TO NEGATE THE NEED FOR RAPID ON-SITE EVALUATION: A RANDOMIZED CONTROL TRIAL

Implementing Agency
University of the Philippines - Philippine General Hospital, Department of Medicine
Project Description
Endoscopic ultrasound guided fine needle aspiration (EUS FNA) is a key component for the investigation and diagnosis of solid pancreatic masses.  It has a proven track record for being safe with complications and tumour seeding being a rare occurrence.  The sensitivity, specificity and diagnost . . .
Cooperating Sponsor
None
Date of Registration
14 July 2022
Region
NCR
Sources of Monetary or Material Support
Self-funded
Primary Outcomes

Diagnostic yield of EUS FNA with ROSE versus EUS FNB without ROSE for solid pancreatic masses.

Health Condition(s) or Problem(s) Studied

Pancreatic tumors

Pancreatic cancer

Endoscopic ultrasound (EUS) guided fine needle aspiration (FNA) or biopsy  (FNB) of pancreatic tumors.

Rapid onsite evaluation (ROSE) of biopsy/aspiration samples

 


ASPIRE Study: Prescription Pattern and Healthcare Utilization after SABA-Challenged Environment Implementation

Implementing Agency
AstraZeneca Pharmaceuticals (Philippines) Inc.
Project Description
It is a multi-centre, multi-country, observational study, the primary objective of this study are the following:   To evaluate the proportion of SABA reduction from 3 or more canisters to less than 3 canisters per year in chronic asthma patients with SABA overuse and pre-i . . .
Date of Registration
13 July 2022
Region
NCR
Sources of Monetary or Material Support
AstraZeneca Pharmaceuticals (Philippines) Inc.
Primary Outcomes
Primary Objectives1. To evaluate the proportion of SABA reduction from 3 or more canisters to less than 3 canisters per year in chronic asthma patients with SABA overuse and pre-index exacerbations, 12 months before and over 12 months after the implementation of the program.2. Given t . . .
Health Condition(s) or Problem(s) Studied

Bronchial Asthma


Results 11 - 20 of 1105
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