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EFFICACY OF DRY HYDROGEN PEROXIDE TECHNOLOGY IN REDUCING MICROBIAL COLONIZATION IN THE AIR AND HIGH TOUCH AREAS IN A TERTIARY HOSPITAL IN THE PHILIPPINES
A better understanding of what organisms are circulating in the Isolation Rooms while the patients are admitted would be able to evaluate the risk of the patients and their caregivers to these infectious agents. A devise such as DHP (Synexis TM) as an adjunct to regular cleaning of the rooms may be able to attempt to reduce exposure and control the disease.
A Phase 2/3 Randomized, Controlled, Open-Label Study of KRT-232 in Subjects With Primary Myelofibrosis (PMF), Post-Polycythemia Vera MF (Post-PV-MF), Or Post-Essential Thrombocythemia MF (Post-ET-MF) who are Relapsed or Refractory to Janus Kinase (JAK) Inhibitor Treatment
The proportion of subjects in each arm achieving SVR of ≥ 35% at Week 24 by MRI/CT scan (central review)
Primary Myelofibrosis (PMF), Post-Polycythemia Vera MF (post-PV-MF), or Post-Essential Thrombocythemia MF (post-ET-MF)
Etonogestrel subdermal implant for the management of endometriosis-associated pain after ovarian-sparing surgery
Postoperative medical management of pelvic endometriosis
A study to test whether different doses of BI 690517 alone or in combination with empagliflozin improve kidney function in people with chronic kidney disease
Treatment of Diabetic or Non-Diabetic Chronic Kidney Disease
A multicenter, randomized, double-blind, placebo-controlled Phase II/III trial to evaluate the efficacy, safety and immunogenicity of the recombinant two-component COVID-19 vaccine (CHO cell) in adults aged 18 years andolder.
Prevention of Coronavirus Disease 2019 (COVID-19) caused by infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
A Randomized, Double-Blind, Placebo-Controlled Phase 2/3 Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of ANX005 in Subjects with Guillain Barré Syndrome (GBS)
This study is intended to evaluate the efficacy and safety of ANX005 administered by intravenous (IV) infusion to participants recently diagnosed with Guillain-Barré Syndrome (GBS). The total duration of study participation is approximately 6 months.
Guillain-Barré Syndrome (GBS)
The clinical efficacy and safety of midpoint transverse process to pleura block versus thoracic paravertebral block for postoperative analgesia among patients undergoing modified radical mastectomy: A non-inferiority double blind randomized controlled trial
This is a research proposal in developing a new alternative technique to the thoracic paravertebral block. The midpoint transverse process to pleura block (MTP) is promising in terms of safety and efficacy which is classified as a novel paraspinal technique. This study aims to determine the clinical efficacy of MTP, being a non-inferior alternative to paravertebral block. Cadaveric studies and case reports have been published about MTP. This will be the first double blinded non inferior randomized controlled trial that will take effect in a 14th month duration in the national university hospital, University of the Philippines-Philippine General Hospital. This new intervention will deliver good immediate post-operative analgesia, which is associated with lower risk of developing chronic pain, which can lead to a significant reduction of hospital stay and facilitate early discharge. The use of narcotics for pain relief will be reduced leading to reduced incidence of nausea and vomiting. It will lead to a better quality of life, physically and mentally.
A 24-week, multicenter, randomized, double-blind, parallel-arm, placebo-controlled extension study to assess the safety of CSJ117, when added to existing standard of care asthma therapy in patients ≥18 years of age who completed study CCSJ117A12201C
TSLP (Thymic Stromal Lymphopoietin)
A 12-week randomized, participant-and investigator-blinded, placebo-controlled, parallel group study to explore the efficacy, pharmacodynamics, safety, and pharmacokinetics of two doses of inhaled CSJ117 in adults with Chronic Obstructive Pulmonary Disease (COPD)
The primary objective of this study is to assess the effect of CSJ117 on disease/symptom burden after 12 weeks of treatment in patients with COPD. The primary clinical question of interest is whether CSJ117 in comparison to placebo provides symptom relief to COPD.
Chronic Obstructive Pulmonary Disease (COPD)
EPIK-B4: A Phase II, multicenter, randomized, open-label, active-controlled study to assess the safety and efficacy of dapagliflozin + metformin XR versus metformin XR during treatment with alpelisib (BYL719) in combination with fulvestrant in participants with HR+, HER2-, advanced Breast Cancer with a PIK3CA mutation following progression on/after endocrine-based therapy
Treatment of HR+, HER2-, advanced Breast Cancer with a PIK3CA mutation following progression on/after endocrine-based therapy