Unspecified
Studies on Selected Medicinal Plants in Mindanao
PHRR121108-000013
Extraction, Purification and Preliminary Toxicity and Antioxidant Potential Assessment of the Phytochemicals from Selected Medicinal Plants of Mindanao
This project is part of the first phase of a program which ultimately aims to produce herbal preparations or pure therapeutic drug leads sourced out from medicinal plants found in Mindanao. The first phase of this program is exploratory and holistic in nature in the sense that all plant extracts will be subjected to general bioassays (cytotoxicity, antioxidant, antimicrobial, DNA-binding, genotoxicity and adulticidal) which are correlated with important diseases (cancer, infectious diseases including MRSA, TB and malaria). Bioassay-guided fractionation and purification will ensue for “active” extracts after evaluation of their bioactivities. Identification of the active components will then follow. For this project, three studies are involved: Study 1: Extraction and Purification of the Phytochemicals Study 2: Toxicity Screening of the Crude Extracts Study 3: Evaluation of the Comparative In Vitro Antioxidant Potentials of the Crude Extracts
| Regime | Classification | Priority |
|---|---|---|
| 2010 - 2016 | Health Technology Development | Drug Discovery and Development |
| Start Date | Duration in Months | Target Completion Date | Actual Completion Date |
|---|---|---|---|
| 2012-06-01 | 12 | 2013-06-01 | 0000-00-00 |
Ongoing
| Institution | Classification | Region | LTO # |
|---|---|---|---|
| Mindanao State University - Iligan Institute of Technology, College of Science and Mathematics | Public Higher Education Institution - State Universities and Colleges | Region X |
| Institution | Region |
|---|---|
| Philippine Council for Health Research and Development, Department of Science and Technology | NCR |
| Name | Institution and Institution Address | |
|---|---|---|
| Dr. Mylene M. Uy | mylene603@yahoo.com | Chemistry Department, MSU-Iligan Institute of Technology, Andres Bonifacio Avenue, 9200 Iligan City |
| Name | Institution and Institution Address | |
|---|---|---|
| Dr. Mylene M. Uy | mylene603@yahoo.com | Chemistry Department, MSU-Iligan Institute of Technology, Andres Bonifacio Avenue, 9200 Iligan City |
| Name | Expertise | Affiliation |
|---|---|---|
| Anita P. Rivera | Biochemistry | Mindanao State University - Iligan Institute of Technology, College of Science and Mathematics |
| Mylene M. Uy, PhD | Natural Products Chemistry | Mindanao State University - Iligan Institute of Technology, College of Science and Mathematics |
Non-clinical Studies
cancer, infectious diseases including MRSA, TB and malaria
Unspecified
Unspecified
- Philippines