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Submitted: 16 May 2017 Modified: 16 May 2017
HERDIN Record #: PCHRD1705160853239

The first MIBG therapy in the Philippines.

1Patricia A. Bautista,
2Jonas Francisco Y. Santiago
Department of Nuclear Medicine and PET - St. Luke's Medical Center

Abstract

Neuroblastoma is an embryonal tumor of children that frequently presents with metastases. Our patient is a 6-year-old girl who was diagnosed to have neuroblastoma with diffuse metastatic disease throughout the skeleton as seen in her 123I-MIBG scan in the United States. 18F-FDG PET/CT scan was done in the Philippines after chemotherapy and gene therapy, and before 131I-MIBG therapy. No additional lesions were seen on PET.  131I-MIBG was then performed and an 131I-MIBG with SPECT/CT thereafter, which showed an increase in size and extent of the lesion in the head and a decrease in number of the skeletal metastases. New 131I-MIBG-avid posterior cervical lymph nodes were also localized through SPECT/CT. For this patient, a follow-up 123I/131I-MIBG scan would be more cost-effective in assessing response to therapy. Sectional imaging may be done to obviate the need for sedation of this young patient.

1.
Publication Type:
Journal
Publication Sub Type:
Case report
Title:
The Philippine Journal of Nuclear Medicine
Frequency:
Semi-Annual
Publication Date:
January-June 2015
Volume:
10
Issue:
1
Page(s):
24-27
Publisher:
Philippine Society of Nuclear Medicine

LocationCall NumberAvailable FormatAvailability
Philippine Council for Health Research and Development Library Box No.21 Fulltext Print Format (Request Document)