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Submitted: 24 March 2017 Modified: 17 May 2017
HERDIN Record #: PCHRD17032416064654

An unusual case of lupus vulgaris and the use of interferon-gamma release assay (Quantiferon-TB Gold test) as an aid in supporting the diagnosis.

1Natividad Sandra D. Chua,
2Maria VIctoria Rosabelle M. Rovira
Department of Dermatology - St. Luke's Medical Center

Abstract

Lupus vulgaris is a cutaneous form of tuberculosis, which may persist for years unless treated. This is a relatively rare condition, the diagnosis of which can be challenging especially when it presents in areas that are not common predilection sites. In the western region, it is more often seen on the head and neck. Among Asians, it is more often seen on the trunk, knees, and elbows. It rarely occurs on the arms and legs. This is a case of a 55-year old Filipino woman with a solitary non-pruritic, non-tender, erythematous to dusky red plaque on the left anterior leg, which elicited an "apple-jelly" color on diascopy. Skin punch biopsy revealed granulomatous dermatitis. Purified protein derivative (PPD) and interferon-gamma release assay (Quantiferon TB-Gold) tests revealed positive results for tuberculosis infection. Based on morphology and laboratory results, she was diagnosed to have lupus vulgaris and was enrolled under the Department of Health's Tuberculosis-Directly Observed Treatment Short-course Program (TB-DOTS), and was treated successfully.

1.
Publication Type:
Journal
Publication Sub Type:
Case report
Title:
St. Luke's Healthcare Journal
Frequency:
Semi-Annual
Publication Date:
July-December 2016
Volume:
11
Issue:
2
Page(s):
94-98
Publisher:
St. Luke's Medical Center

LocationCall NumberAvailable FormatAvailability
Philippine Council for Health Research and Development Library Box No. 35 Fulltext pdf (Request Document)