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Submitted: 05 January 2017 Modified: 05 January 2017
HERDIN Record #: NCR-PHC-1701051043488

Pulmonary hypertension secondary to acyanotic congenital heart disease, a Philippine Heart Center experience.

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Pulmonary arterial hypertension (PAH) is a recognized complication of congenital heart defects that are characterized by chronic left-to-right shunting, and the status of the pulmonary vascular bed often is the principal determinant of the clinical manifestations, course, and feasibility of surgical treatment. This, however, can also occur from a variety of pulmonary and noncardiovascular conditions.


The role of cardiac catheterization for diagnosis and treatment of pulmonary hypertension  is very important. When mean pulmonary artery pressure increased more than 25 mmhg, then PAH is defined. But this is measured accurately only by the catheterization. The etiolgy of PAH is diagnosed as left-sided heart failure, if pulmonary capillary wedge pressure (Ppcw) is increased more than 13 mmhg by blood oxygen saturation set-up, and pulmonary vascular  resistance of more than 3 Wood units.


A total of 252 patients were included in this study. The degree of pulmonary hypertension was classified through 2D-echocardiogram and cardiac catheterization. Patients underwent surgical repair of their respective cardiac lesion and pulmonary arterial pressure was again measured post-operatively. PAP improved post-op in some patients especially those with mild to moderate pulmonary hypertension.

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Research Project
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Philippine Heart Center Medical Library PHC.R.027.02 Fulltext (Download)

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