OBJECTIVES: This study aims to determine the sensitivity, specificity, positive predictive value and negative predictive value of Computerized Dynamic Posturography (CDP) in properly labeling patients with peripheral vestibular disorders by Videonystagmography (VNG) as having vestibular dysfunction.
Design: Case - Control Study
Setting: Tertiary Private Hospital
Subjects: Twenty-three (23) patients aged 18 and above with no history of hypertension or cardiovascular disease and no intake of anti-vertigo medications for at least 48 hours prior to testing and with complete VNG and CDP results obtained on the same day or at least two days apart were included in the study. Cases were defined as those diagnosed with a peripheral vestibular disorder by VNG while controls were defined as those with normal VNG results. Sensitivity, specificity, positive predictive value and negative predictive value of CDP in labeling those with peripheral vestibular disorders as vestibular were determined using VNG as gold standard.
RESULTS: There were 11 cases (4 males, 7 females) and 12 controls (8 males, 4 females). Using VNG as the gold standard for diagnosing peripheral vestibular disorders, CDP had a sensitivity of 45.45% and specificity of 66.67% with Positive Predictive Value(PPV) of 55.56% and Negative Predictive Value(NPV) of 57.14% in assessing peripheral vestibular disorders among the adults tested. Interestingly, 33.33% of patients with normal VNG may actually have had a vestibular dysfunction that could be detected by CDP.
CONCLUSION: Prospective studies with larger sample sizes utilizing VNG and CDP are recommended in order to verify our findings.