Therapeutic options for molluscum contagiosum rely primarily on destructive measures such as surgery and electrocautery. Curettage and cryotherapy are fairly effective, but the pain and emotional trauma associated with these procedures make them undesirable for use in the pediatric population.
To determine the efficacy, safety and acceptability of topical application of 0.1% tretinoin cream in the treatment of molluscum contagiosum.
STUDY DESIGN: Open clinical trial
STUDY SETTING: Tertiary Government Hospital (Jose R. Reyes Memorial Medical Center)
STUDY POPULATION: Thirty-two (32) patients with molluscum contagiosa
The patients were given 0.1% Tretinoin cream (Stieva A) applied twice a day to molluscum contagiosa lesions for a period of four weeks or until clinical remission.
Complete or no resolution of molluscum contagiosa lesions.
Out of 32 patients who enrolled in this study, only 11 patients completed the clinical trial. There was negative cure in the eleven patients. All of them developed retinoid dermatitis. Patients were not satisfied with the treatment trial.
0.1% Tretinoin cream is fairly tolerable but not effective nor acceptable for the treatment of molluscum contagiosum.