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Submitted: 16 August 2011 Modified: 16 August 2011
HERDIN Record #: PCHRD08161101081780

The efficacy of various modalities of treatment in the different subsets of stone formers.

1Marieta B. De Luna
University of the Philippines - Philippine General Hospital, UP-PGH


Two hundred three (203) kidney stone formers were prospectively analyzed by the Renal Section of the Philippine General Hospital from January 1986 to December 1990. One hundred fifty six (156/203 or 76.85

) were between 30 and 60 years old when first seen by a nephrologist. Male to female ratio was 1.42:1.00. Stone analysis was done in one hundred eleven (111) patients. The most common chemical component of kidney stones was calcium, found as a pure salt in fifty one patients (51/111 or 45.95

). Metabolic analysis for hypercalciuria and hyperuricosuria was completed in one hundred seventy nine (179) patients. Hyperuricosuria was identified in seventy three (73/179), thirty with pure hyperuricosuria and forty three with a combined hypercalciuric problem. Among the hypercalciurias, absorptive hypercalciuria type II was most commonly identified (56/179) followed by renal leak (37/179). No metabolic abnormality was defined by Pak could be identified in forty five (45/179) patients. urine citrate levels were determined by ion chromatography in eighty five (85) stone patients and forty seven (47) non-stone formers. Hypocitraturia ( or

of stone patients. It was identified in 18/23 patients initially classified as having "no metabolic abnormality". Hypocitraturia was significantly associated with frequent stone recurrence.

Publication Type:
Research Project
January 1, 1986-December 31, 1990


The study sought to: (1)identify metabolic abnormality for classification of subsets of urolithiasis among Filipino kidney patients; (2)determine the distribution of the different types of urolithiasis; and (3)determine the different therapeutic modalities as to their efficacy in treating and preventing stone occurrence.

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