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Submitted: 15 August 2011 Modified: 15 August 2011
HERDIN Record #: PCHRD08151104085921

Mutagenicity potential of mahogany seeds .

Clara L. Sylianco

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Mutagenicity studies were done on a decoction of mahogany seeds, its alcoholic extract and mahogany seeds lipid layer using the Ames Test, Rec Assay and Micronucleus Test. These did not show direct DNA-damaging capacity. No genotoxicity was observed before metabolic activation on the neutralized sample, the alcoholic extract, and the lipid layer. However, genotoxicity before metabolic activation was observed with the decocotion. No chromosome breaking effect was observed.

Publication Type
Research Project
Date

Objectives

To determine the mutagenicity potential of mahogany seeds using the Rec Assay, Ames Test, Micronucleus Test and Host-Mediated Assay.

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Philippine Council for Health Research and Development Library Abstract Print Format (Request Document)

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