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Submitted: 16 May 2007 Modified: 11 April 2013
HERDIN Record #: PCHRDPC940680

Electrophysiologic and anatomic substrate for paroxysmal atrial fibrillation.

1Jo Ann S. Lao ,
2Raul Lastimosa ,
3William T. Chua

Abstract

The mechanism initiating paroxysmal atrial fibrillation (PAF) has been shown to be triggered by spontaneously occurring atrial premature contraction (APC). The ability of the coupling index of the APC and underlying anatomic pathology to influence the onset of the arrythmia was analyzed in this study
Included were randomly selected 14 consecutive patients, who on 24-hour Holter monitoring, demonstrated PAF triggered by APCs with shorter coupling indices. The second group of randomly selected 14 consecutive patients showed longer coupling indices of APC without subsequent PAF initiation. However, occasional shorter coupling indices were observed without PAF initiation. The echocardiographic studies of the forer group showed a variety of anatomic pathology ranging from regional wall motion abnormally to valvular nature. In contrast, all patients in the second group had normal echocardiographic studies. It is concluded in this study that coupling indices of APC per se do not take all credence but an underlying anatomic substrate remains a major pivotal framework for initiating PAF.

1.
Publication Type:
Journal
Publication Sub Type:
Journal Article, Original
Title:
Philippine Journal of Cardiology
Frequency:
Quarterly
Publication Date:
July-September 1993
Volume:
21
Issue:
3
Page(s):
1129-1132
Publisher:
Philippine Heart Association

LocationCall NumberAvailable FormatAvailability
Philippine Council for Health Research and Development Library Box No.44 Fulltext Print Format (Request Document)
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