From January to July 31,1989, there were 774 operations performed in the Department of Surgery. Among these patients, 446 are males and 328 females. Most of the patients operated upon belong to the second to the fourth decade of life. Elective operations (n=625) comprise 80.7
of all operative procedures while emergency operations (n=149) account only for 19.3
There are 61 cases of infected surgical wound infection rate of 7.8
(61/774). The most common aerobic organisms isolated are gram negative microbes. The top 6 organisms are Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, Acinetobacter calcoaciticus, Enterobacter cloacae and Enterobacter agglomerans comprising 80
of all isolates.After arbitrarily setting the acceptable level of antimicrobial activity at 75
, only amikacin, ceftazidime, ceftriaxone, ciprofloxacin and aztreonam exhibited considerable activity against most leading organisms. The commonly used antibiotics have poor antimicrobial activity against Staphylococcus aureus and Enterobacter cloacae. For Pseudomonas aeruginosa, only amikacin, ceftazidime and cifrofloxacin show moderate antimicrobial activity. For infections caused by Eschericia coli, ceftazidime and ciprofloxacin show excellent activity while ceftriaxone and aztreonam are found to be fairly effective agaisnt it. Acinetobacter calcoaciticus showed excellent susceptibility to amikacin while enterobacter agglomerans showed moderate susceptibility to this drug.
To prospectively survey the microbiological etiology of surgical wound infection encountered in the Department of Surgery and analyze the antimicrobial activity pattern of commonly used antibiotics in the hospital.