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Submitted: 15 December 2007
HERDIN Record #: PCHRD121507031209

Determination of myocardial function using doppler tissue imaging in patients with acute myocardial infarction.

Mercedita Parazo,
Edwin S. Tucay,
Raul D. Jara,
Joyce S. Jumangit,
Sharon Marisse Lacson

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BACKGROUND: This study was undertaken to determine the myocardial function using Doppler tissue imaging in patients with acute myocardial infarction and to correlate the mitral E/E' velocity ratio with die patients' Killip classification of congestive heart failure secondary to acute myocardial infarction (AMI). 60 patients with AMI either a non-ST segment elevation myocardial infarction (NSTEMI) or ST elevation myocardial infarction (STEMI) were studied. Ejection fraction (EF), transmitral and pulmonic vein velocities, and mitral annular velocities were measured by conventional echocardiography and Doppler tissue imaging (DTI), respectively. These values were correlated with the Killip heart failure classification of the patients. 39(65 percent) patients had NSTEMI and 21(35 percent) patients had STEMI. There were no significant difference in mitral annular and pulmonic vein velocities in subjects with NSTEMI and STEMI with EF<50 when analyzed by paired t test. However, there was a significant difference in mitral annular and pulmonic vein velocities in subjects with NSTEMI and STEMI with EF>50 percent. The mitral E/A ratio and E/E' ratio were significantly higher in the NSTEMI EF>50 percent group. The E/E' ratio was correlated widi the Killip classification categories. Post hoc tests showed an E/E' ratio of <5 is significandy correlated (p value<0.05) to Killip I classification. And an E/E' ratio of > 15 is significandy correlated (p value <0.05) to Killip IV classification. There was a weak correlation of E/E' ratio range of 5-10 and 10-15 to the Killip classification. DTI can be used in the quantitative evaluation of the regional LV wall motion velocities among patients with acute myocardial infarction. Systolic and diastolic function can readily be assessed. The combined transmitral E velocity and annular E' velocity or die E/E' ratio is correlated to the patient's Killip classification for congestive heart failure. A ratio of <5 strongly correlate to a Killip I classification and a ratio of > 15 strongly correlate to a Killip IV classification. The E/E' ratio did not show discriminatory power in differentiating patients in Killip II and III classification. (Author)

Publication Type
Journal
Publication Sub Type
Journal Article, Original
Title
Philippine Journal of Cardiology
Frequency
Semi-Annual
Publication Date
January-June 2006
Volume
34
Issue
1
Page(s)
19-27

Objectives

General Objective:

To determine the myocardial function using Doppler tissue imaging in patients with acute myocardial infarction.

Specific Objectives:

To correlate the myocardial function as measured by DTI, specifically the mitral E/E' velocity ratio with the patients' Killip classification of congestive heart failure secondary to acute myocardial infarction (AMI).

To determine the association of the lateral and medial mitral annuli velocities through DTI with the patients' Killip classification of congestive heart failure secondary to acute myocardial infarction.

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Philippine Council for Health Research and Development Library Abstract Print Format (Request Document)

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