Background: Determination of optical weaning period and method is important in the management of intubated patients. Several studies have been done to determine the best mode of weaning, still no consenus has been made as to the most efficient mode of weaning.
Methods: A randomized controlled trial will be conducted for 2 years. All intubated patients referred to Pulmonary service of Philippine Heart Center will be initially subjected to trial of two-hour spontaneous breathing. Those who cannot tolerate the procedure wil be randomized to 5 weaning methods: adaptive support ventilation, synchronized intermittent mandatroy ventilation, pressure support ventilation, once daily trial of spontaneous breathing and intermittent trial of sponatneous breathing. Success rate will be determined for each weaning method to verify which is the best method applicable in our setting.
Results: 89 (89.89%) of intubated patients were successfully extubated after a trial of two-hour spontaneous breathing. Only 10 patients (10%) were randomized to Adaptive suprport ventilation (2), synchronized intermittent mandatory breathing (2), pressure support ventilation (2), once daily trial of spontaneous breathing (2), and intermittenttrials of spontaneous breathing (2). The difference in group characteristics and the outcome of weaning cannot be computed yet due to inadequate data.
Conclusion: The best method of weaning can't be determined yet because of insuficiency of data.