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Submitted: 13 July 2008
HERDIN Record #: PCHRD071508010747

Glandular cardiac myxoma: A histochemical case study of the glandular epithelium and review of literature .

Arlene M. De Luna,
Rico P. Lasaca,
Carmela D. Tan,
Felipe S. Templo Jr

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Background ÃÆ'Æ'Æ’ÃÆ'†â€™ÃÆ'Æ'â€Ã...¡ÃÆ'‚¢ÃÆ'Æ'Æ’ÃÆ'¢â‚¬Ã...¡ÃÆ'Æ'¢ÃÆ'¢â‚¬Ã...¡ÃÆ'‚¬ÃÆ'Æ'Æ’ÃÆ'¢â‚¬Ã...¡ÃÆ'Æ'¢ÃÆ'¢â€Ã...¡Ã‚¬ÃÆ'‚ A glandular component in cardiac myxoma is uncommon. We described a case of a glandular cardiac myxoma removed from the right atrium in a 43 year old woman. Histopathologic evaluation revealed a typical cardiac myxoma with classic stellate cells disposed singly while some displaying cellular syncytia set in a loose myxoid matrix admixed with several benign mucin-producing glandular luminal structures. The glandular cells demonstrated strong histochemical reactivity with Periodic Acid-Schiff with diastase, mucicarmine, alcian blue at pH 2.5 and colloidal iron which revealed presence of acidic, simple, non-sulfated, sialic, epithelial type of mucin within the tumor. The presence of these glandular structures within a cardiac myxoma unless recognized as part of the tumor may lead to the difficulty and erroneous interpretation of a metastatic mucinous adenocarcinoma, thus, familiarization with this histo-logic variant coupled with special stains and careful clinical history, can help provide a correct interpretation of this lesion. (Author)

Publication Type
Journal
Publication Sub Type
Case report
Title
Philippine Heart Center Journal
Frequency
Quarterly
Publication Date
April-June 2006
Volume
12
Issue
2
Page(s)
44-48
LocationLocation CodeAvailable FormatAvailability
Philippine Council for Health Research and Development Library Abstract Print Format (Request Document)