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Submitted: 04 August 2016 Modified: 05 October 2016
HERDIN Record #: NCR-PHC-16080410413228

Tetralogy of fallot: clinical course of post-operative total correction a ten-year follow-up.




Background: Early operative outcome of Tetralogy of Fallot (TOF) was excellent. However, long-term complications for patients following TOF correction was still an issue. The objective of this study was to determine the post-operative complications ten years after total repair of Tetralogy of Fallot.


Methods: A retrospective ten-year follow-up among pediatric patients admitted at the Philippine Heart Center from year 2000 to 2005 who underwent Tetralogy of Fallot correction.


Result: With a total of 41 subjects, the median for timing of TOF repair was 1.9 years old. Twenty-four percent of the total correction involved transannular patching, while 9.8% had creation of monocusp of the pulmonary valve. Complications after TOF repair with transannular patching included mild pulmonary regurgitation (57%), mild residual RVOT obstruction (28%), reoperation (7%), and pulmonary valve replacement (PVR) (14%). After PVR, follow-up echocardiography showed mild PR, and improved right ventricular systolic function. Without transannular patching, echocardiographic finding showed mild PR (41%) and no residual right ventricular outflow tract obsruction (32%). Complete heart block (9%) and reoperation (4.5%) were also noted as complications after transannular patching.


Conclusion: Although, majority of the population are asymptomatic ten years after TOF repair, thorough clinical assessment along with diagnostic work-up should be done regularly to monitor development of possible complications.

Publication Type
Research Report
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Philippine Heart Center Medical Library PHC.R.003.15 Fulltext Print Format