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Submitted: 10 December 2015 Modified: 10 December 2015
HERDIN Record #: CAR-UCBCF-15121008044147

Agathis dammara (Lamb.) L. C. Rich from the Cordillera Region, Philippines and its antibiotic properties.

Ronan Baculi,
Teodora Balangcod,
Rosemary Gutierrez,
Nardo Pastor,
Timothy Puma-at


















































































Indigenous people use plants for folkloric medicine in the Cordillera
Region, Philippines. This study determines if Agathis dammara 
which is used for folkloric medicine have antimicrobial or antibiotic
properties since the resin of the plant is  being used for the treatment of 
arthritis and bronchial asthma. A. dammara crude extracts and resin 
were evaluated for their antimicrobial properties by the standard disc
diffusion assay using the test  for microorganisms: Escherichia coli, 
subtilis, Staphylococcus aureus, Proteus vulgaris, Candida albicans and
Aspergillus flavus. The Minimum Inhibitory Concentrations (MICs) of the
plant resin against test bacteria were determined. Phytochemical 
screening of the plant resin was also undertaken. Varying concentrations
of crude leaf extracts and resin of Agathis dammara were found to
have very active, active to partially active antibacterial properties. MIC
determination revealed that Bacillus subtilis was more sensitive to the 
A. dammara extract since the organism scored the lowest value of MIC
(62.5 µg/ml). Escherichia coli, Proteus vulgaris and Staphylococcus aureus
scored higher MIC values of 125 µg/ml. Phytochemical screening 
revealed the presence of alkaloids, steroids, anthraquinones, 
flavonoids, saponins, tannins and polyphenols. Statistical analyses 
revealed that crude leaf extracts and resin of A. dammara were 
found to have active to partially active antibacterial properties using
the standard disc diffusion assay which were further confirmed by the
MIC tests and phytochemical screening. Therefore, the A. dammara
leaf extract used in the study has antibiotic properties which could be 
the basis why the plant is being used for folkloric medicine specifically
for treatment of arthritis and bronchial asthma.

Publication Type
Others
Place of Publication
Khon Kaen, Thailand
Publication Date
2015

Objectives




























This study determines if Agathis dammara 
which is used for folkloric medicine have antimicrobial or antibiotic
properties since the resin of the plant is  being used for the treatment of 
arthritis and bronchial asthma. A. dammara crude extracts and resin 
were evaluated for their antimicrobial properties by the standard disc
diffusion assay using the test  for microorganisms: Escherichia coli, 
subtilis, Staphylococcus aureus, Proteus vulgaris, Candida albicans and
Aspergillus flavus.