Background of the Study: Increase in survival of premature infants due to improvement in neonatal care, has brought about conditions that can bring complications affecting the patient's quality of life. Development of retinopathy of prematurity leading to blindness if left untreated is brought about by various factors both fetal and maternal, risk factors for ROP in this institution were determined.
Objectives: To determine the associated risk factors for retinopathy of prematurity in preterm infants delivered in DLSUMC from 2007 to 2012
Reseach Design: Analytic Cross Sectional Study
Patient/ Subject Selection: All infants admitted at the Neonatal Intensive Care Unit from January 2007 to January 2012 with the diagnosis of Prematurity tested for Retinopathy of Prematurity
Outcome Measure: Risk factors of all the infants that tested positive for retinopathy of prematurity were obtained. Risk factors determined were Maternal Factors, Neonatal Factors, Nutrition and Level of Oxygenation.
Result: A total of 53 preterm infants were screened for Retinopathy of Prematurity over the 5 year study period. Twenty three (23) tested positive for ROP. The risk factors for retinopathy of prematurity that were significant in this study were: maternal comorbidities (pvalue 0.0910, OR: 0.8, 90% CI: 0.1-9.2), age of gestation (pvalue 0.0970, OR: 2.1, 90%; CI: 0.6 to 7.7), birth weight (pvalue 0.0640, OR: 1.5; 90% CI: 0.0640), oral feeding (pvalue 0.0620, OR: 3.0; 90% CI: 1.1-8.1), and duration of O2 support (pvalue 0.0610, OR 3.2, 90% CI: 1.1-8.8).
Conclusion: This study reaffirmed that the development of retinopathy is multifactorial and an interplay of both fetal and maternal factors.
Key words: Retinopathy of Prematurity, ROP, fetal risk factors, maternal risk factors, premature infants, preterm infants.