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Submitted: 16 May 2007 Modified: 15 August 2019
HERDIN Record #: PCHRDPC971554

Use of plasmapheresis in Filipino patients with Guillain-Barre syndrome.

 Bernal-Dantes M,
 Giongco-Baylon H

In summary, our local experience with therapeutic plasmapheresis among 13 adult patients revealed the following data: there were two deaths which were most likely due to complications of the severe disease process. A significant number of the survivors (10 out of 11) improved completely or substantially, achieving independent ambulation (clinical grade 2) or having only minor signs and symptoms (clinical grade 1). The remaining survivor, although not regaining unassisted walk, had improved his motor function. Once recovery began in all patients, this was sustained throughout the follow-up. The time to achieving independent ambulation and the time spent on a respirator seemed to be substantially shorter than those reported in foreign literature. However, we had dealt with a small number of patients who had severe GBS. A larger, randomized, controlled trial will be necessary to make definite conclusions.

It must be emphasized that accurate diagnosis, careful monitoring, the best medical nursing, supportive care and active rehabilitation still constitute the essentials of management in GBS. Plasmapheresis further improves the outcome in the more severely affected or worsening patients with GBS of recent onset, and it remains as an invaluable tool in this entity.(Summary)

Publication Type
Update: J Continuing Educ Med Practitioners
1996 Jan-Mar
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