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Submitted: 16 May 2007
HERDIN Record #: PCHRDPC040353

T-cell primary CNS lymphoma in an immunocompetent 50 year old female presenting as a brainstem lesion.

 Cuanang, Joven R,
 Lo, Raymundo W,
 Aquino, Juanito MS J

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BACKGROUND: Primary CNS lymphoma (PCNSL) is a non-Hodgkins lymphoma that arises within and limited to the cranial to the cranial-spinal axis in the absence of evident localization outside the nervous system. Once an extremely rare neoplasm comprising around 1 percent of all brain tumors, this lymphoma has generated interest due to its rising incidence in both immunocompromised and immunocompetent hosts and its responsiveness to systemic chemotherapy. Beginning in the 90s, the incidence is 1:100,000 and presents with a variety of clinical symptoms and signs making initial diagnosis difficult. There is a preponderance of men with the peak incidence in the fifth through seventh decades and affects frequently the cerebral hemispheres. Involvement of the brainstem is unusual. It is almost always a B-cell type; T-cell lymphomas of the nervous system do occur but rarely. (Author)

Publication Type
Journal
Title
The Philippine Journal of Neurology
Frequency
2002 Jun
Publication Date
Page(s)
0
LocationLocation CodeAvailable FormatAvailability
Philippine Council for Health Research and Development Library Abstract Print Format (Request Document)