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Submitted: 05 July 2018 Modified: 17 August 2018
HERDIN Record #: NCR-SBU-18070514254990

Apple cider vinegar consumption as an adjunct therapy incontrolling blood glucose levels: A systematic review of its effect on glycemic profile.

Maria Reina  D. Abu,
Louise  C. Manangan,
Ranielle A. Ongoco,
Ryan  J. Pan,
Princess Mae  P. Pelisco ,
Mark  I. Reyes,
Christoffer  T. Samarista,
Dannah Jeanne J. Tagulao,
Joseph Christian  M. Tigas,
Gerben Villanueva,
Michael  Van Haute

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BACKGROUND: Diabetes appears to be a health issue in most countries specially here in the Philippines due to increasing population growth, aging, urbanization, and increasing prevalence of obesity and physical inactivity. Recently, the use of apple cider vinegar as a health remedy has been tremendously increasing. It is now widely used as an alternative medicine for systemic illnesses like hypercholesterolemia, hypertension and diabetes. The effect of vinegar on blood sugar levels is perhaps the best researched and the most promising of apple cider vinegar's possible health benefits. Several studies have found that vinegar may help lower glucose levels.  Some reports showed that vinegar affect the glucose and insulin responses to a sucrose or starch load.


OBJECTIVE:  The general objective of this study is to determine the relevance of regular intake of apple cider vinegar as an adjunct in controlling blood glucose levels. Specifically, it aims to assess the effect of apple cider vinegar on glycemic profile (fasting blood sugar, HbA1c) amongindividuals with or without comorbidities - based on the results of the studies included.


SELECTION CRITERIA: Only randomised and cross-over clinical trials in individuals were included. Interventions include apple cider vinegar at any dose or duration versus placebo, anyhypoglycemic agents, or no intervention. The trials could be double blind, single blind, or unblinded. Trials could be unpublished or published.


DATA COLLECTION AND ANALYSIS: Various electronic databases will be employed in this study which includes but not limited to PubMed, Medline, Clinical Key, Google Scholar, Cochrane, UpToDate; searched abstracts and lists of reviewed articles. Furthermore, reference lists of published studies and review articles will also be searched manually for additional studies. Studies included were from 2010 up to 2017 regardless of publication and language. A criterion of methodological quality will be used to assess and appraise the clinical trials included in this study. The Review Manager 5.3 will be used to assess weighted mean difference using 95% confidence interval.

Publication Type
Research Report
Date
March 7, 2018

Publication Type
Research Report
Date
LocationLocation CodeAvailable FormatAvailability
San Beda University - Health Sciences Library Fulltext
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