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Submitted: 22 March 2017 Modified: 22 March 2017
HERDIN Record #: R10-MSUIIT-17032208450493

Antioxidant Activity, Total Phenolic Content, and GC-MS Analysis of the root of Kawilan (EmbeliaphilippinensisA. DC.).

Nyzar Mabeth  O.  Odchimar,
Olga M.  Nuñeza,
Mylene  M.  Uy,
W.T.P.S.K.  Senarath

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The root of "kawilan" (Embeliaphilippinensis) is known by the Talaandig tribe of Bukidnon, Philippines to cure tumors, cysts, and few types of cancer yet it lacks scientific authentication of its medicinal properties. In the present study, the antioxidant activity of aqueous and methanol extracts of E. philippinensis roots was evaluated by determining the free radical scavenging activity using 2,2 diphenyl-2-picrylhydrazyl hydrate (DPPH)assay method and substantiated by total phenolics content (TPC) by Folin-Ciocalteu's assay method. GC-MS analysis of methanol extract was also performed to identify the specific semi-volatile chemicals present. Both aqueous and methanol root extracts showed high DPPH inhibition activity at high concentrations. However, the aqueous root extract of E. philippinensis showed higher DPPH inhibition activity than methanol root extract. The TPC assay showed higher phenolics content on the methanol extract. Furthermore, GC-MS analysis revealed the presence of bioactive compounds with known antioxidant properties: (a) 9,12- octadecadienoic acid, methyl ester, (b) eicosane, (c) hexadecane (d) hexadecanoic acid, methyl ester, (e) 9, 12, octadecatrienoic acid, (Z,Z), (f) 9, 12, 15- octadecatrienoic acid, (Z,Z,Z), (g) n-hexadecanoic acid, (h) squalene, (i) phenol, 2,4-bis (1,1-dimethyl), and (j) 1,2-benzenedicarboxylic acid, bis (2-methylpropyl) ester. Results indicate that E. philippinensis possesses antioxidant properties, which may account for its folkloric medicinal uses

Publication Type
Bulletin of Environment, Pharmacology and Life Sciences
Publication Date
April 2016
LocationLocation CodeAvailable FormatAvailability
Office of the Vice Chancellor for Research and Extension, Mindanao State University-Iligan Institute Technology Fulltext External Link (View)

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