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Submitted: 09 January 2015 Modified: 22 August 2019
HERDIN Record #: NCR-UERMMMC-15010908145476

A non-concurrent cohort study on the use of Euphorbia hirta Linn (tawa-tawa) in dengue: patients' platelet response.

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Methods A non-concurrent cohort design was used. The cohort group comprised 46 verified dengue patients who had taken Euphorbia hirta during the course of the illness and 47 subjects in the control group who did not. Subjects in the cohort group were interviewed regarding the use of Euphorbia hirta. Platelet counts were compared within and between the cohort and control groups.


Results The use of Euphorbia hirta in the cohort group varied in terms of its preparation, dosage, frequency and duration of intake. Controlling for day of illness, the mean platelet counts did not show significant differences between the groups. However percentage change of platelet counts at each day of illness was favorable among the Euphorbia hirta subjects compared to the control group. The initial drop in platelets during the first 4 days of illness was greater in the control group. The rise beginning day 5 and 6 was twice greater in the Euphorbia hirta group compared to the control group.


Conclusion The beneficial effect of Euphorbia hirta may be on the degree of change in platelet levels experienced by the cohort group. The expected decline during the initial days of illness was less precipitous and the rise in platelet level was twice greater compared to the control group.

Publication Type
Journal
Publication Sub Type
Journal Article, Original
Title
The Health Sciences Journal
Frequency
Others
Publication Date
January-June 2014
Volume
3
Issue
1
Page(s)
9-14
LocationLocation CodeAvailable FormatAvailability
UERMMMC Fulltext Print Format
Philippine Council for Health Research and Development Fulltext pdf (Request Document)
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