We have evaluated the analgesia efficacy of IV paracetamol and diclofenac sodium during the first 16 hours after abdominal hysterectomy in a placebo controlled double-blind study. We studied 30 patients receiving intrathecal morphine after a standardized anesthetic, allocated randomly to receive IV paracetamol 500 mg, diclofenac 75mg and placebo after wound closure and at 8 and 16 hours. Mean and standard deviation were used to describe the data. Kruskal-Wallis Test and Mann-Whitney tests (non-parametric tests) for ordinal data were used to compare pain scores. A 95% confidence level was considered significant (p<0.05). All subjects included in the study underwent abdominal hysterectomy (TAHBSO), for myoma uteri. Mean age of patients for each group did not differ significantly. Proportion of subjects reporting scores of 3 and below at 16th hour was significantly different among the three groups - 100% of subjects in the paracetamol group, 40% in the diclofenac group and none in the placebo group.