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Submitted: 16 October 2012
HERDIN Record #: R04A-DLSHSI-12101516132197

Association of renal ultrasound, voiding cystourethrography findings with renal scintigraphy findings in children with urinary tract infection.

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OBJECTIVES: To evaluate the association between renal ultrasound findings, voiding cystography (VCUG) findings with Renal scan in infants and children with confirmed urinary tract infection, and determine any possible clinical features which may predispose such patients to the risk of developing renal scar formation.
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DESIGN: Case-control study
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SETTING: Tertiary Medical Center
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MATERIALS & METHODS: Medical records of pediatric patients with confirmed or culture proven urinary tract infection from July 1997 to June 2005 were retrieved. Demographic data, urine culture and results of imaging studies were collected, tabulated and analyzed. Odds ration was used to determine the association between renal ultrasound, voiding cystourethrography and renal scintigraphy findings. Level of significance was placed at p value of ? 0.05.
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RESULTS: Fifty-one (51) patients comprising of 102 renal units were included in the study with age ranging from 1 month old to 14 years old with a male to female ration of 1:1.55. Fever was the most common clinical manifestation, followed by vomiting and diarrhea. E.coli was the most common pathogen isolated from the urine. There was no association noted with regards to age, sex, clinical manifestations and etiologic organism with the development of renal scar. Twenty-seven (26.5%) renal units have abnormal renal ultrasound; 12 (11.8%) of which have renal scar on renal scintigraphy. Fourty-three (42.6%) renal units have vesicoureteal reflux (VUR); 25 (24.3%) of which have renal scar. Of the fourty-nine (57.9%) renal units with no VUR, 5 (4.9%) of them have renal scar of renal scintigraphy. Statistical analysis using odds ratio showed significant association between VCUG and renal scintigraphy (p-value 0.000) while renal ultrasound and renal scintigraphy showed no significant association (p-value 2.533)
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CONCLUSION: Results revealed that there is a direct association between renal ultrasound and VCUG findings with renal scan findings such that an abnormal renal ultrasound and VCUG results could probably give an abnormal renal scan result. Children presenting with urinary tract infection regardless of age, sex , clinical manifestations and offending organism should undergo both renal ultrasound and VCUG to identify a patient at risk of developing renal scar.

Objectives

To evaluate the association between renal ultrasound findings, voiding cystography (VCUG) findings with Renal scan in infants and children with confirmed urinary tract infection, and determine any possible clinical features which may predispose such patients to the risk of developing renal scar formation.

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