Two hundred three (203) kidney stone formers were prospectively analyzed by the Renal Section of the Philippine General Hospital from January 1986 to December 1990. One hundred fifty six (156/203 or 76.85
) were between 30 and 60 years old when first seen by a nephrologist. Male to female ratio was 1.42:1.00. Stone analysis was done in one hundred eleven (111) patients. The most common chemical component of kidney stones was calcium, found as a pure salt in fifty one patients (51/111 or 45.95
). Metabolic analysis for hypercalciuria and hyperuricosuria was completed in one hundred seventy nine (179) patients. Hyperuricosuria was identified in seventy three (73/179), thirty with pure hyperuricosuria and forty three with a combined hypercalciuric problem. Among the hypercalciurias, absorptive hypercalciuria type II was most commonly identified (56/179) followed by renal leak (37/179). No metabolic abnormality was defined by Pak could be identified in forty five (45/179) patients. urine citrate levels were determined by ion chromatography in eighty five (85) stone patients and forty seven (47) non-stone formers. Hypocitraturia ( or
of stone patients. It was identified in 18/23 patients initially classified as having "no metabolic abnormality". Hypocitraturia was significantly associated with frequent stone recurrence.
The study sought to: (1)identify metabolic abnormality for classification of subsets of urolithiasis among Filipino kidney patients; (2)determine the distribution of the different types of urolithiasis; and (3)determine the different therapeutic modalities as to their efficacy in treating and preventing stone occurrence.