Report an error   


Submitted: 16 May 2007 Modified: 06 April 2013
HERDIN Record #: PCHRDPC011194

Left Ventricular diastolic filling doppler indices is a useful adjunct in the interpretation of dobutamine stress echocardiogram.

Grace Casaclang ,
Louwe Go ,
Marietta Crisostomo ,
Gregorio Rogelio,
Mary Ann Lao M,
Homobono Calleja

See More

BACKGROUND: In coronary occlusion or heart failure, abnormal relaxation of the left ventricle is the earliest manifestation
OBJECTIVE: To measure the Doppler derived diastolic indices from baseline to peak dose dobutamine and compare patients with normal (Group I) and abnormal (Group II) wall motion
DESIGN: Case control study of patients who undergo DSE
METHODS: Doppler signals of transmitral blood flow were obtained at baseline and peak dobutamine stress
The following were measured:
Peak early filling velocity E - peak early left ventricular filling velocity (cm/s)
Peak atrial filling velocity A -- velocity of atrial contraction (cm/s)
Peak early to atrial velocity ratio (E/A) - relative contribution of early and late ventricular filling
E acceleration time - rate of increase of E velocity stet (m/s2)
E decceleration time - rate of stet of velocity following E velocity (m/s2)
Total diastolic VTI - velocity time integral (cm)
Isovolumic relaxation time (IVRT) - time from aortic valve closure to mitral valve opening (ms)
Corresponding heart rate - heart rate at time Doppler indices were obtained during baseline and peak dose dobutamine
RESULTS: Patients with normal wall motion and contractility have increased E and A velocities, faster E deceleration time and E acceleration time. The E/A ratio and VTI are unchanged. The IVRT is decreased. Patients with segmental wall motion abnormality have decreased E velocity, unchanged E deceleration time. The E acceleration time may be unchanged. The A velocity is increased. The E/A ratio and IVRT are reduced. The TI is unchanged antihypertensive was doubled.

Publication Type
Journal
Publication Sub Type
Journal Article, Original
Title
Philippine Journal of Cardiology
Frequency
Quarterly
Publication Date
July-September 1999
Volume
27
Issue
3
Page(s)
96-100
LocationLocation CodeAvailable FormatAvailability
Philippine Council for Health Research and Development Library Box No. 44 Fulltext Print Format (Request Document)
1. Sholnick, David , Segar, Douglas . "Asessment of diatolic function with echocardiography" ACC Current Journal Review , 47-49, March 1997-April 1997
2. Nishimura, R , Tajik, Jamil . "Evaluation of diastolic filling of left ventricular in health and disease: dopper echocardiographic is the clinicians Rosetta Stone" JACC 30, 8-18, 1997
3. Labovitz, Lewen M. "Evaluation of left ventricular systolic and diastolic dysfunction during transient myocardial ischemia produced by angioplasty" JACC 10, 748-55, 1987
4. Go, L . "Evaluation of left ventricular diastolic fucntion by doppler echocardiography " Phil Journal of Cardiovascular Medicine 12, 36-37, 1999
5. El-Said, E , Roelandt, J . "Abnormal left ventricular early diastolic Filling during dobutamine stress doppler echocardiography is a sensitive indicator of significant coronary artery disease" Eur Heart J 24, 1618-24, 1997
6. El-Said, ESM , Fioretti, PM , Roelandt, JRTC . "Dobutamine stress doppler echocardiography bedore and after coronary angioplasty" Eur Heart J 14, 1011-21, 1993
7. Voutilainen, S , Kupari, M . "Factors influencing doppler indexes of left ventricular filling in healthy persons" Am J Cardiol 68, 653-659, 1991
8. Harrison, M , Clifton, D . "Effect of heart rate on left ventricular diastolic transmitral flow velocity patterns assessed by doppler echocardiography in normal subjects" Am J Cardiol 67, 622-627, 1991
9. Masuyama, T , Masaaki, MD . "Abnormal coronary flow dynamics at rest and during tachycardia associated with impaired left ventricular relaxation in humans: implications for tachycardia induced ischemia" JACC 24(7): 1625-32, December 1994

Copyright © One Window Project 2018. All rights reserved.