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Submitted: 16 May 2007 Modified: 12 April 2018
HERDIN Record #: PCHRDPC040650

Reconstruction of the infrarenal aorta using a fascia-peritoneal patch graft in pigs.

1Anthony Manlulu,
2Jonathan Nolasco,
3Edgar Palacol,
4Imelda Palacol,
5Stephanie Santos,
Section of Thoracic and Cardiovascular Surgery, Department of Surgery - St. Luke's Medical Center

Abstract

Vascular reconstruction utilizing autologous vein grafts may require additional incisions for harvesting. Synthetic prosthetic grafts are associated with an increased risk of infection.
OBJECTIVE: We present an alternative method of aortic reconstruction using autologous fascia and peritoneum as a patch graft.
METHODS: Fascia-peritoneal patch grafts were used to repair an infrarenal aortic defect in 5 landrace pigs. The subjects underwent re-laparotomy at specific intervals with excision of the grafted aortic segment. The specimens were examined utilizing hematoxylin and eosin stain, special stains for elastin (Weigerts stain), collagen (Massons Trichrome stain) and immunohistochemical stain for factor VIII.
RESULTS: In all specimens, no thrombosis was noted and graft patency was 100 percent. Endothelialization was apparent at 7 days, however, factor VIII stain failed to light up the endothelial cells in all specimens. Elastin and collagen formation were noted in the patch graft at 28 days as shown in Weigerts and Massons Trichome stain.
CONCLUSION: Fascia-peritoneal patch graft can be used as an alternative method of aortic reconstruction with excellent patency rates and no wound complications.

1.
Publication Type:
Journal
Publication Sub Type:
Journal Article, Original
Title:
Philippine Journal of Surgical Specialties
Frequency:
Quarterly
Publication Date:
January-March 2003
Volume:
58
Issue:
1
Page(s):
9-13
Publisher:
Philippine College of Surgeons

LocationCall NumberAvailable FormatAvailability
Philippine Council for Health Research and Development Library Box No. 6 Fulltext pdf (Request Document)
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