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Submitted: 16 May 2007 Modified: 22 July 2019
HERDIN Record #: PCHRDPC980840

A review of adrenal insufficiency cases at the Philippine General Hospital (1989-1993).

Concepcion F. Pizarro-Noche,
Zonita C. Borlongan,
Marita M. Fuentes,
 Lim-Abraham MA

Twenty-nine cases of adrenal insufficiency were admitted to the Philippine General Hospital from January 1989 to December 1993. Seventeen charts were available for review. The patients ages ranged from 18 to 70 years old with a mean age of 46 years. Twelve (71%) were males while five (29%) were females. The most common form of adrenal insufficiency is of the secondary type and the most common cause of this is Hypothalmus-Pituitary-Adrenal Axis suppression due to chronic intakes of steroids for other medical disorders of which Dexa- methasone appears to be the most commonly implicated preparation. Post-partum necrosis and pituitary tumor are the other commonly encountered causes. The most common symptom was body weakness (94%) followed by easy fatigability (82%), anorexia (76%), and syncope (71%). Hypotension was present in 59% of cases. Hyponatremia and hyperkalemia were present only in 38% and 18% of cases respectively. Early recognition of the endocrine problem with prompt administration of intravenous Hydrocortisone to severly hypotensive patients obviates what could be a fatal outcome.

Publication Type
Journal
Publication Sub Type
Journal Article, Original
Title
Philippine Journal of Internal Medicine
Frequency
Semi-Annual
Publication Date
May-June 1998
Volume
36
Issue
3
Page(s)
75-80
LocationLocation CodeAvailable FormatAvailability
Philippine Council for Health Research and Development Library Box No.47 Fulltext Print Format (Request Document)
Philippine Council for Health Research and Development Fulltext pdf (Request Document)

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