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Submitted: 16 May 2007 Modified: 22 January 2019
HERDIN Record #: PCHRDPC980306

The efficacy of prednisone in tuberculous pleural effusion.

Louella Araza ,
Rosario Aceron ,
Marian Celis ,
Fortunato Gomez ,
Inocencio H. Lopez ,
Lavernie Jacobo ,
Joy Gulmatico ,
Jean Tenefrancia ,
Ma. Victoria Masculino ,
Cecilia Cercado

This is a systematic randomized case control study of patients with tuberculous pleural effusion admitted at Western Visayas Medical Center to determine the efficacy of Prednisone in the management of tuberculous pleural effusion. During the 10-month study period, 12 cases were included in the study who fulfilled the following: patients 15 years old and above manifesting signs and symptoms suggestive of tuberculosis, patients with tuberculous pleural effusion diagnosed by radiographic and pleural fluid examination and patients with tuberculous pleural effusion graded 20-60%. Using the t-test, there was early regression of tuberculous pleural effusion and early resolution of clinical symptoms such as cough and dyspnea in the experimental group than the control group. None of the patient developed the recognized side effects of steroids, however, some patients complained of tolerable epigastric pain. Thus, Prednisone as an adjunctive therapy to anti- TB medications in the management of tuberculous pleural diffusion causes early improvement of clinical symptoms and hastened regression of tuberculous pleural effusion, hence, invasive procedures were avoided and lessened the financial burden of the patient.

Publication Type
Journal
Publication Sub Type
Journal Article, Original
Title
Philippine Journal of Internal Medicine
Frequency
Semi-Annual
Publication Date
November-December 1997
Volume
35
Issue
6
Page(s)
241-247
LocationLocation CodeAvailable FormatAvailability
Philippine Council for Health Research and Development Library Box No. 47 Fulltext Print Format (Request Document)
Philippine Council for Health Research and Development Fulltext pdf (Request Document)

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