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Submitted: 16 May 2007 Modified: 09 September 2019
HERDIN Record #: PCHRDPC970128

Enteric fever: A review of 31 cases at the Ospital ng Makati.

Ma. Teoliza  O. Almendras ,
Felicismo V. Agas Jr

Enteric fever is gm (-) bacillary infection with protean manifestation s. In the Philippines, it remains to be a major health problem. Although enteric fever is one of the more extensively studied disease in the world today, reported clinical features diagnostic of the disease vary widely This retrospective study aimed to determine the epidemiologic distribution of the disease, describe the most common clinical manifestation and review the different antimicrobial agents used in diagnosed cases of enteric fever at the Ospital ng Makati from November 1990-1994 Thirty one (31) patients with a (+) blood culture for S. typhi were included in this study. There were 20 males (64.5) and 11 females (35.45%) with ages ranging from 16.56 yrs. Highest percentage of cases were seen during the rainy season, among students and laborers and along the Guadalupe area in Makati. Most common presenting symptoms were flu-like and GI manifestations, while pulse-fever diproportion and abdominal tenderness were the predominant signs. Laboratory features were non-specific. Chloramphenicol was still the most commonly used drug in our setting. Nine (29.03%) out of the 31 cases developed complications, most common of which is intestinal hemorrhage. One patient developed intestinal perforation which eventually became our lone mortality in this study. We were also able to document 2 cases of S. typhi strains resistant to first line antibiotics Physicians, including primary heatlh care workers, need to be aware of the emergence of multidrug resistant strains of S. typhi. Rational and discriminate use of antimicrobials should be osberved in the light of these developments. The need for improved sanitation, safe water supply and patient education however, cannot be overemphasized, if we hope to prevent and contain the spread of the disease in the future.

Publication Type
Publication Sub Type
Journal Article, Original
Philippine Journal of Internal Medicine
Publication Date
July-August 1995
LocationLocation CodeAvailable FormatAvailability
Philippine Council for Health Research and Development Library Box No. 46 Fulltext Print Format (Request Document)
Philippine Council for Health Research and Development Fulltext pdf (Request Document)

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