Report an error   


Submitted: 16 May 2007 Modified: 05 January 2015
HERDIN Record #: PCHRDUP920178

Glucose-6-phosphate dehydrogenase deficiency in malaria endemic areas in the Philippines.

1Nelia P. Salazar,
2Marietta C. Baccay ,
3Myrna R. Acacio ,
4 Echiverri CP,
5Fermin A. Talao ,
6Andres S. Cubacub ,
7Crispin  P. Echiverri,
8Adoracion Z. Reyes

Abstract

Glucose-6-phosphate dehydrogenase (G-6-PD) deficiency, a hereditary biochemical defect of erythrocytes, was detected among residents of malaria endemic areas on the big island of Luzon, Republic of the Philippines. A total of 774 individuals were examined, 1.5 to 68 years old consisting of 485 males and 289 females. The overall prevalence rate of 5.5% among Filipinos concurred with data from previous studies. Pedigrees of selected families showed a Mendelian pattern of inheritance. The potential hazard of treating G-6-PD deficient patients with antimalarials such as primaquine, sulfonamide, sulfones, quinidine, and quinine, or combination thereof, is recognized. (Auth)

1.
Publication Type:
Journal
Publication Sub Type:
Announcements
Title:
Record of Achievements Technical Cooperation Proje
Publication Date:
Page(s):
0

2.
Publication Type:
Research Project
Date:

LocationCall NumberAvailable FormatAvailability
Philippine Council for Health Research and Development Library Fil RA440.5 R31 1988 Abstract Print Format (Request Document)
Philippine Council for Health Research and Development Library RDR RA 56 B12 Abstract Print Format (Request Document)