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HERDIN Record #: PCHRD012608010125 Submitted: 26 January 2008

The role of duration of abdominal pain,WBC and neutrophil count in predicting complications in acute appendicitis.

Antonio B. Buban

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This is a retrospective study design to determine the association of duration of abdominal pain in hours,WBC and neutrophil count on the development of complications among patients with acute appendicitis admitted and operated at MCU-FDTMF hospital form January 1,2002 to December 31,2003.Urinalysis and complete blood count were performed at the time of admission.Patients were followed up by serial physical examination up to the time of operation.The primary outcome of interest was complications of acute appendicitis.A total of 185 patients were included in the study.The mean age in patients with uncomplicated and complicated acute appendicitis was 26.62and 30.67 respectively.Theres is a predominance of male patients,with 1.01:1 ratio.Majority of patients(88.6 percent)were diagnosed based on clinical grounds.Only 21 patients had ultrasound as additional ancillary procedure.There were significant differences in the means of uncomplicated and complicated acute appendicitis based on the duration of abdominal pain,WBC count,neutrophil count,and hospital stay.Univariate analysis shows that the duration of abdominal pain,WBC count,and sex are significant predictors for the development of complications of acute appendicitis (p value<0.05).Multivariate analysis shows that the duration of abdominal pain increases the risk of developing complications of acute appendicitis by 1.10(95 percent CI=1.06-1.13;p value=0.000).Sex was the only variable considered as actual cofounder on the development of complications of acute appendicitis was 92.2 percent and the risk of developing complication was 19 times(95 percent CI=5.45 65.91,p value=0.000).Duration of abdominal pain is a good predictor of complication of acute appendicitis.

Publication Type
Research Report
Date
November 30, 2003

Objectives

General Objective:To determine the association of duration of abdominal pain and the development of complications(gangrenous and perforation)of acute appendicitis among patients admitted and operated at MCU-FDTMF hospital from January 1,2002 to December 31,2003.
Specific Objectives:To determine the sensitivity ans specificity of duration abdominal pain in predicting complications of acute appendicitis among patients admitted and operated at MCU-FDTMF hospital from January 1,2002 to December 31,2003.

LocationLocation CodeAvailable FormatAvailability
Manila Central University-Filemon D. Tanchoco Memorial Foundation 340 Abstract
 

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