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Submitted: 01 April 2013 Modified: 04 March 2019
HERDIN Record #: PCHRD13040114441149

Applicability of the hour of life approach of hyperbilirubinemia among Filipino term infants: Progress report.

Ma. Esterlita V. Uy

Hyperbilirubinemia is one of the leading causes of morbidity in the newborn. Previously considered a benign condition, there is much concern in this area due to the worldwide resurgence of kernicterus, which is the ultimate manifestation of every severe hyperbilirubinemia. Mortality rates of kernicterus are at 50% with the survivors having sequelae like cerbral palsy, mental retardation, hearing loss and others. The American Academy of Pediatrics guidelines on hyperbilirubinemia emphasize closer monitoring in infants, including a discharge bilirubin level among infants at risk to determine likelihood of subsequent significant hyperbilirubinemia. Other key health-societal practices on hyperbilirubinema are lactation support, timing of first follow-up, surveillance, and risk management.


Hospitals in the US have begun using a transutaneous bilirubinometer which is a non-invasive, painless procedure to determine bilirubin levels. However, some concern has arisen regarding the reliability of the bilirubinometer's readings among dark colored skin infants. The first part of this study is undertaken to determine the reliability of the transcutaneous bilirubinometer against serum level among Filipino infants. One hundred six infants 37-42 weeks age of gestation have been recruited. Serum and transcutaneous bilirubin levels have been taken simultaneously. Results show a very high correlation between transcutaneous bilirubin and serum bilirubin. The coefficient of determination of serum bilirubin and transcutaneous bilirubin are: forehead: 0.88 and sternal area: 0.91. The transcutaneous bilirubin especially sternal measurement is an excellent non-invases screening tool to determine bilirubin levels among Filipino infants.

Publication Type
Journal
Publication Sub Type
Journal Article, Original
Title
The University of the Philippines Manila Journal
Frequency
Monthly
Publication Date
October 2011
Volume
14
Page(s)
21
LocationLocation CodeAvailable FormatAvailability
Philippine Council for Health Research and Development Library Pro 276 Fulltext Print Format (Request Document)
Philippine Council for Health Research and Development Abstract pdf (Request Document)

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